Leukotriene C4 (LTC4) is a potent mediator of immediate hypersensitivity, bronchoconstriction, smooth muscle contraction, increased vascular permeability and epithelial mucous secretion. It is derived from arachidonic acid through the 5-lipoxygenase pathway. Arachidonic acid is first converted to 5-hydroperoxy derivative which is then transformed to Leukotriene A4 (LTA4). Enzymatic addition of glutathione to LTA4 produces LTC4.
This is an ELISA (Enzyme-Linked Immunosorbent Assay) for the quantitative analysis of Leukotriene C4 levels in biological fluid. This test kit operates on the basis of competition between the enzyme conjugate and the Leukotriene C4 in the sample for a limited number of binding sites.
|Leukotriene B4||< 0.01%|
|Prostaglandin A2||< 0.01%|
|Prostaglandin B2||< 0.01%|
|Prostaglandin D2||< 0.01%|
|Prostaglandin E2||< 0.01%|
|Prostaglandin F2α||< 0.01%|
|6-keto-Prostaglandin F1α||< 0.01%|
|6-trans-Leukotriene B4||< 0.01%|
|20-0H-Leukotriene B4||< 0.01%|
|Thromboxane B2||< 0.01%|
|Product #||Product Description|
|406210||Leukotriene C4, 96 well kit|
Kit inserts available on our website are for reference use only and are subject to change. It is always recommended to use the protocol included with the kit.
Calculation of Results
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