Corticosterone is a glucocorticoid secreted by the adrenal cortex in response to stress. Glucocorticoids are also essential for proper metabolism of fats, proteins, and carbohydrates in the body. While cortisol and corticosterone are both produced in response to stress in humans, corticosterone is the predominant glucocorticoid produced in mice and rats. Corticosterone has also been used as a predictor of stress in a variety of wild animals. In particular corticosterone levels were increased in Galapagos marine iguanas under famine conditions brought on by El Niño.
While not always predictive of environmental stress in the wild, conditions such as starvation, rapid temperature change, or changes in daily routine can cause increased corticosterone levels in laboratory mice and rats.
Corticosterone is also administered to treat inflammation because like many other steroids, it is a powerful anti-inflammatory agent.
Standard Curve in EIA Buffer
|Product #||Product Description|
|402810||Corticosterone Kit, 96 well kit|
Kit inserts available on our website are for reference use only and are subject to change. It is always recommended to use the protocol included with the kit.
Calculation of Results
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