Cortisol, or hydrocortisone, is the primary corticosteroid secreted by the adrenal cortex. Cortisol is synthesised from cholesterol and may be found in the blood as free Cortisol or bound to corticosteroid-binding globulin. The release of Cortisol is controlled by ACTH, which is produced in the anterior pituitary. Plasma Cortisol levels are highest in the morning and decrease throughout the day. Cortisol concentration in the plasma also elevates in response to stress. Cortisol has an anti-inflammatory effect and aids in carbohydrate metabolism, renal function and the promotion of glucogenesis.
Measurement of plasma Cortisol levels is useful in diagnosing conditions related to functions of the adrenal cortex, including Cushing's syndrome (hypercortisolism), Addison's disease (hypocortisolism) and adrenal tumours. Abnormal Cortisol levels may also possibly be linked to prostate cancer, depression, and schizophrenia.
Standard Curve in EIA Buffer
|Product #||Product Description|
|402710||Cortisol Kit, 96 well kit|
Kit inserts available on our website are for reference use only and are subject to change. It is always recommended to use the protocol included with the kit.
Calculation of Results
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